EDTA Chelation Benefits – Scientific References

EDTA Chelation Therapy Alone and in Combination with Oral High-Dose Multivitamins and Minerals for Coronary Disease: The Factorial Group Results of the Trial to Assess Chelation Therapy

References

1. Clarke NE, Clarke CN, Mosher RE. Treatment of angina pectoris with disodium ethylene diamine tetraacetic acid. Am J Med Sci. 1956;232(6):654–666. [PubMed]
2. Grier MT, Meyers DG. So much writing, so little science: A review of 37 years of literature on Edetate Sodium chelation therapy. Ann Pharmacother. 1993;27:1504–1509. [PubMed]
3. Lamas GA, Goertz C, Boineau R. Effect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: the TACT randomized trial. JAMA. 2013 Mar 27;309(12):1241–50. [PMC free article] [PubMed]
4. Escolar E, Lamas GA, Mark DB. The Effect of an EDTA-based Chelation Regimen on Patients With Diabetes Mellitus and Prior Myocardial Infarction in the Trial to Assess Chelation Therapy (TACT). Circ Cardiovasc Qual Outcomes. 2014;7:15–24. [PMC free article] [PubMed]
5. Rozema TC. Special issue: protocols for chelation therapy. J Adv Med. 10:5–100. 997.
6. Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis. J Am Med Assoc. 2007;297(8):842–857. [PubMed]
7. Sasso HD, Christen WG, Bubes V, et al. Multivitamins in the prevention of cardiovascular disease in men: the Physicians’ Health Study II randomized controlled trial. JAMA. Nov 7. 2012;308(17):1751–60. [PMC free article] [PubMed]
8. Lamas GA, Goertz C, Boineau R, et al. Design of the trial to assess chelation therapy (TACT). Am Heart J. 2012;163(1):7–12. [PMC free article] [PubMed]
9. Lamas G, Boineau R, Goertz C, et al. Oral High-Dose Multivitamins and Minerals After Myocardial Infarction. A Randomized, Controlled Trial. Ann Intern Med. 2013;159:797–804. [PMC free article] [PubMed]
10. Kalbfleisch JD, Prentice RL. The Statistical Analysis of Failure Time Data. Second Edition John Wiley & Sons, Inc; New York: 2002.
11. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Statist Assn. 1958;53:457–481.
12. Cox DR. Regression models and life-tables (with discussion). J Royal Statist Soc B. 1972;34:187–220.
13. Costa J, Borges M, David C, Vaz Carneiro A. Efficacy of lipid lowering drug treatment for diabetic and non-diabetic patients: meta-analysis of randomised controlled trials. BMJ. 2006;332:1115–24. [PMC free article] [PubMed]
14. Tellez-Plaza M, Guallar E, Fabsitz RR, et al. Cadmium exposure and incident peripheral arterial disease. Circ Cardiovasc Qual Outcomes. 2013;6:626–33. [PMC free article] [PubMed]
15. Menke A, Muntner P, Batuman VV, Silbergeld EK, Guallar E. Blood lead below 0.48 μmol/L (10 μg/dL) and mortality among US adults. Circulation. 2006;114(13):1388–1394. [PubMed]
16. Nawrot TS, Staessen JA. Low-level environmental exposure to lead unmasked as silent killer. Circulation. 2006;114:1347–9. [PubMed]
17. Monnier VM. Transition metals redox: reviving an old plot for diabetic vascular disease. J Clin Invest. 2001;107:799–801. [PMC free article] [PubMed]
18. Nagai R, Murray DB, Metz TO, et al. Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications. Diabetes. 2012;61:549–59. [PMC free article] [PubMed]
19. Frizzell N, Baynes JW. Chelation therapy: overlooked in the treatment and prevention of diabetes complications? Future Med Chem. 2013;5:1075–8. [PubMed]
20. Cranton EM, Liu ZX, Smith IM. Urinary Trace and Toxic Elements and Minerals in Untimed Urine Specimens. In Textbook on EDTA Chelation Therapy. 2nd Ed. Hampton Roads Publishing Co; Charlottesville, VA: 2001. pp. 503–539.
21. Agarwal S, Zaman T, Tuzcu EM, Kapadia SR. Heavy metals and cardiovascular disease: results from the National Health and Nutrition Examination Survey (NHANES) 1999-2006. Angiology. 2011;62(5):422–429. [PubMed]
22. Levine GN, Frei B, Koulouris SN, Gerhard MD, Keaney JF, Jr, Vita JA. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1996;93(6):1107–1113. [PubMed]
23. Bailey RL, Gahche JJ, Lentino CV, Dwyer JT, Engel JS, Thomas PR, et al. Dietary supplement use in the United States, 2003-2006. J Nutr. 2011;141:261–6. [PMC free article] [PubMed]

References
1 Harte, J., et al. Toxics A To Z: A Guide To Everyday Pollution Hazards (Berkeley, CA: University of California Press, 1991), 103.
2 Harte, J., et al. Toxics A To Z: A Guide To Everyday Pollution Hazards (Berkeley, CA: University of California Press, 1991), 34-6.
3 Kellas, B., Ph.D., and Dworkin, A., N.D. Surviving the Toxic Crisis (Olivenhain, CA: Professional Preference Publishing, 1996), 186.
4 Lewis, H. Technological Risk (New York: W.W. Norton, 1990), 125.
5 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 149.
6 Kellas, B., Ph.D., and Dworkin, A., N.D. Surviving the Toxic Crisis (Olivenhain, CA: Professional Preference Publishing, 1996), 187, 217, 230-34.
7 Casdorph, H., M.D., and Walker, M., D.P.M. Toxic Metal Syndrome (Garden City Park, NY: Avery Publishing, 1995), 95.
8 Kellas, B., Ph.D., and Dworkin, A., N.D. Surviving the Toxic Crisis (Olivenhain, CA: Professional Preference Publishing, 1996), 177.
9 Weiner, M. The Way of the Skeptical Nutritionist (New York: Macmillan, 1981). Elemental Analysis (Asheville, SC: Great Smokies Diagnostic Laboratories, 1999), 4.
10 Casdorph, H., M.D., and Walker, M., D.P.M. Toxic Metal Syndrome (Garden City Park, NY: Avery Publishing, 1995), 120.
11 Crapper-McLachlan, D.R., and DeBoni, U. “Aluminum in human brain disease—an overview.” Neurotoxicology 1 (1980), 3-16. Crapper-McLachlan, D.R., and Van 12 Berkum, M.F.A. “Aluminum: a role in degenerative brain disease associated with neurofibrillary degeneration” in Progress in Brain Research, Vol. 70, D.F. Swaab et al., Eds. (Amsterdam: Elsevier Science Publishers, 1986), 399-409.
12 Harte, J., et al. Toxics A To Z: A Guide To Everyday Pollution Hazards (Berkeley, CA: University of California Press, 1991), 246-47.
13“U.S. plans a system for tracking levels of lead in children’s blood.” New York Times (August 29, 1992), 10.
14“Schools Warned of Lead in Water Fountains.” Associated Press, Washington, D.C. (April 11, 1989).
15 Winter, M.S. Poisons in Your Food (New York: Crown Publishers, 1991), 187.
16 Zavon, M.R., et al. “Chlorinated hydrocarbons insecticide content of the neonate.” Annals of the New York Academy of Sciences 160 (June, 23, 1969), 196-200.
17 Harte, J., et al. Toxics A To Z: A Guide To Everyday Pollution Hazards (Berkeley, CA: University of California Press, 1991), 49.
18 Kellas, B., Ph.D., and Dworkin, A., N.D. Surviving the Toxic Crisis (Olivenhain, CA: Professional Preference Publishing, 1996), 184.
19 Kellas, B., Ph.D., and Dworkin, A., N.D. Surviving the Toxic Crisis (Olivenhain, CA: Professional Preference Publishing, 1996), 196.
20 Kellas, B., Ph.D., and Dworkin, A., N.D. Surviving the Toxic Crisis (Olivenhain, CA: Professional Preference Publishing, 1996), 196.
21 Huggins, H., M.S., D.D.S. It’s All In Your Head: The Link Between Mercury Amalgams and Illness (Garden City Park, NY: Avery Publishing, 1993), 5-11, 36-37.
22 “Dental group agrees with FDA and EPA on issue of toxic mercury.” Townsend Letter for Doctors 88 (November 1990), 720.
23 Casdorph, H., M.D., and Walker, M., D.P.M. Toxic Metal Syndrome (Garden City Park, NY: Avery Publishing, 1995), 150.
24 Harte, J., et al. Toxics A To Z: A Guide To Everyday Pollution Hazards (Berkeley, CA: University of California Press, 1991), 103. Nutrient Mineral and Toxic Metal Chart (Boulder, CO: Trace Mineral International, 1999). Werbach, M., M.D. Nutritional Influence on Illness (Tarzana, CA: Third Line Press, 1993), 679-80. Toxic Elements (Asheville, SC: Great Smokies Diagnostic Laboratories, 1998). Golan, R., M.D. Optimal Wellness (New York: Ballantine Books, 1995), 39.
25 Brown, P., and Mikkelsen, E. No Safe Place: Toxic Waste, Leukemia, and Community Action (Berkeley, CA: University of California Press, 1990), 182-183.
26 Walker, M., D.P.M., and Shah, H., M.D. Everything You Should Know About Chelation Therapy (New Canaan, CT: Keats Publishing), 37-38.
27 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 114.
28 Foreman, H. “Toxic side effects of EDTA.” J Chron Dis 16 (1963), 319-323.
29 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 74.
30 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 14.
31 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 14.
32 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 17-18.
33 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 17-18.
34 Olszewer, E., and Carter, J. “EDTA chelation therapy: a retrospective study of 2,870 patients.” Journal of Advancement in Medicine Special Issue 2:1-2 (1989), 197-211.
35 Goldberg, B., and the Editors of Alternative Medicine Digest. Alternative Medicine Guide to Heart Disease (Tiburon, CA: Future Medicine Publishing, 1997), 82.
36 McDonagh, E., et al. “an oculocerebrovasculometric analysis of the improvement in arterial stenosis following EDTA chelation therapy.” Journal of Advancement in Medicine Special Issue 2:1-2 (1989), 155-166.
37 Casdorph, H., M.D. “EDTA Chelation therapy: efficacy in brain disorders.” Journal of Advancement in Medicine Special Issue 2:1-2 (1989), 131-153. Alsleben, H., M.D., and Shute, W., M.D. How to Survive the New Health Catastrophes (Anaheim, CA: Survival Publications, 1973).
38 Freeman, R. “Reversible myocarditis due to chronic lead poisoning in childhood.” Arch Dis Child 40 (1965), 389-93.
39 Zelis, R., et al. “Effects of hyperlipoproteinanemias and their treatment on the peripheral circulation.” J Clin Invest 49 (1970), 1007.
40 Schroeder, H., and Perry, H., Jr. “Antihypertensive effects of binding agents.” J Lab Clin Med 46 (1955), 416.
41 Shin, Y. “Cross-linking of elastin in human athersclerotic aortas.” Lab Invest 25 (1971), 121. Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 164.
42 Jacob, H. “Pathologic states of erythrocyte membrane.” University of Minnesota, Hospital Practice (December 1974), 47-9. Soffer, A., et al. “Myocardial response to chelation.” Br Heart J 23 (1961), 690-94.
43 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994), 164-65.
44 Walker, M., D.P.M. The Chelation Way (Garden City Park, NY: Avery Publishing Group, 1990), 54.
45 Walker, M., D.P.M. The Chelation Way (Garden City Park, NY: Avery Publishing Group, 1990), 54.
46 Rath, M., M.D. Eradicating Heart Disease (Copyright 1993, by Matthias Rath, M.D.), 11.
47 Rath, M., M.D. Eradicating Heart Disease (Copyright 1993, by Matthias Rath, M.D.), 11.
48 CASS Principle Investigators and Associates. “Myocardial infarction and mortality in the coronary artery surgery study (CASS) randomized trial.” New England Journal of Medicine 310:12 (March 1984), 750-758.
49 Goldberg, B., and the Editors of Alternative Medicine Digest. Alternative Medicine Guide to Heart Disease (Tiburon, CA: Future Medicine Publishing, 1997), 20-21. Strauts, Z., M.D. “Correspondence re: Berkeley Wellness Letter and chelation therapy.” Townsend Letter for Doctors 106 (May 1992), 382-83.
50 Oral Chelation: The Bright Hope For Heart Health (Old Lyme, CT: Alternative Medical Publishing), 33.
51 Walker, M., D.P.M., and Shah, H., M.D. Everything You Should Know About Chelation Therapy (New Canaan, CT: Keats Publishing), 96.
52 Walker, M., D.P.M. The Chelation Way (Garden City Park, NY: Avery Publishing Group, 1990), 36.
53 Gordon, G., M.D., D.O. , “Chelation Therapy”, Life Enhancement 32(April 1997), 9-10.
54 Lamar, P. “Calcium chelation of athersclerosis—nine years, clinical experience.” Fourteenth Annual Meeting, American College of Angiology, 1968. Oral Chelation: The Bright Hope For Heart Health (Old Lyme, CT: Alternative Medical Publishing), 33.
55 Brecher, Harold and Arline. Forty Something Forever: A Consumer’s Guide to Chelation Therapy and Other Heart-Savers (Herndon, VA: Healthsavers Press, 1992), 161. Walker, M., D.P.M. The Chelation Way (Garden City Park, NY: Avery Publishing Group, 1990), 48.
56 Halstead, B., M.D. “The scientific basis of EDTA chelation therapy.” Summarized in Life Enhancement (February 1998), 8.
57 Walker, M., D.P.M., and Gordon, G., M.D. The Chelation Answer (Atlanta, GA: Second Opinion Publishing, 1994). “Garlic-EDTA Chelator.” Website article at www. life-enhancement.com/garlicEDTA.htm
58 Urinalysis studies conducted by Maile Pouls, Ph.D., and Greg Pouls, D.C., 1998.
59 Cranton, E., M.D. Bypassing Bypass (Trout Dale, VA: Medex Publishers, 1993).
60 Urinalysis studies conducted by Maile Pouls, Ph.D., and Greg Pouls, D.C., 1998 and currently. Thermology studies conducted by Maile Pouls, Ph.D., and Greg Pouls, D.C., 1998 and currently, with Philip Hoekstra III, Ph.D.
61 Balch, James., M.D., and Balch, Phyllis. Prescription for Nutritional Healing (Garden Park City, NY: Avery Publishing, 1997). Golan, R., M.D. Optimal Wellness (New York: Ballantine Books, 1995), 49-50. Roberts, H., M.D. Aspartame (NutraSweet) Is it Safe? (Philadelphia, PA: Charles Press, 1990). Blaylock, R., M.D. Excititoxins, The Taste That Kills (Santa Fe, NM: Health Press, 1997), 214.
62 Cranton, E., M.D. Bypassing Bypass (Trout Dale, VA: Medex Publishers, 1993), 83.
63 Rath, M., M.D. Eradicating Heart Disease (Copyright 1993, by Matthias Rath, M.D.), 196.
64 Klinghardt, D., M.D., P.h.D. “Migraines, seizures, and mercury toxicity.” Alternative Medicine Digest 21 (December-January 1997-98), 64.
65 Klinghardt, D., M.D., Ph.D. “Amalgam/mercury detox as a treatment for chronic viral, bacterial, and fungal illnesses.” Annual Meeting of the International and American Academy of Clinical Nutrition, San Diego, CA, September 1996.
66 Needleman, H., M.D., Landrigan, P., M.D., Raising Children Toxic Free- How to Keep Your Child Safe From Lead, Asbestos, Pesticides, and Other Environmental Hazards (Farrar, Straus & Giroux Publishing, New York, NY, 1994) 38-39.
67 Schauss, A., Ph.D., Minerals and Human Health: The Rationale for Optimal and Balanced Trace Element Levels (Life Sciences Press, Tacoma, WA, 1995) 4-5.